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Sharon Gilad-Gutnick, PhD

Neuroscience of Vision and Plasticity

I am a Research Scientist at M.I.T. in the Department of Brain and Cognitive Sciences and in Project Prakash, studying how the human brain learns to make sense of the visual world around it.

 

My research focuses on cognition, specifically visual perception, development and plasticity. I do this via an interdisciplinary approach, integrating behavioral/ psychophysics data with imaging/computational approaches in order to probe visual mechanisms, such as those driving face- and object-recognition.

 

My extensive academic work on how children learn to see, combined with my involvement in a non-profit working to alleviate preventable blindness, have contributed to my deep passion for combining basic scientific thinking and applied research, in particular for developing and advocating for research-driven education and intervention.

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Focus areas

Faces

In this research I focus on the remarkable humans ability to recognize faces. I explore the limitations of this capacity, particularly in the absence of early visual experiences and tease apart how innate elements interact with learned experiences. I explore potential avenues for improving this ability, even after the critical period for plasticity has closed.

Drawing

Guided by the principle that every child should engage with the world using their unique encoding strategies, my data-driven approach involves quantifying drawing performance and strategy in both typical and atypical visual development. The objective is to reveal representational differences among children with visual impairments and inform evidence-driven adaptations in curriculum delivery.

AI

Leveraging my expertise in human visual development, I collaborate with outstanding researchers unravel the successes and shortcomings of deep neural networks, and enhance their functionality through flexible learning. Approaching the networks as blank slates devoid of visual experience, we draw inspiration from modeling DNN training after the developmental trajectory of human vision.

Project Prakash

Project Prakash logo

Project Prakash, meaning "light" in Sanskrit, is a remarkable initiative that I have had the privilege to be a part of for the past decade. Conceived by my lifelong mentor turned friend, Pawan Sinha, the project addresses the disproportionately large burden of preventable childhood blindness in rural India, typically caused by congenital cataracts. These cataracts, easily treatable at birth in developed countries, lead to years of blindness in these children, until they are identified and treated by our incredible team at the Dr. Shroff's Charity Eye Hospital. Prakash's mission is both humanitarian and scientific, aiming to surgically provide sight to these children while also exploring fundamental questions about how humans learn to see, even late in life.

 

Witnessing the transformative journey of the Prakash children gaining sight and gradually comprehending the visual world has been a profoundly impactful experience for me, shaping me as both a scientist and a mother. But despite hundreds of surgeries and years of research, challenges persist, and there is still much to accomplish. Our dream is to establish a Prakash center with global reach, where we extend our reach both geographically and to children with other developmental disabilities, and continue to explore scientific opportunities on learning and plasticity.

Although I do not work exclusively on Prakash, the majority of my recent and ongoing work addresses questions of visual learning and plasticity, with an underlying common thread of how typical and atypical early visual experience shapes the development of vision and perception later in life. Much of this work is being done with Prakash children, as well as children with other visual impairments.  I am particularly intrigued by examining plasticity in face perception, utilizing drawings as a tool to gain deeper insights into the perceptual experience and visual representation in children with visual impairments, and improving the performance of deep neural networks by replicating early visual experience that are the building blocks of human development.

If you are interested in learning more about the scientific discoveries that have emerged from working with children who begin to see late in life, as well as challenges faced and our vision for the future, please check out this recent review that I published in PIBBS:


Gilad-Gutnick, S., (2023). Project Prakash: Merging Basic Science and Societal Service in Vision Research. Policy Insights from Behavioral and Brain Sciences, 10(2), 287-295. [full text]

Selected Publications

Gilad-Gutnick, S. (2023). Project Prakash: Merging Basic Science and Societal Service in Vision Research. Policy Insights from Behavioral and Brain Sciences, 10(2), 287-295. https://doi.org/10.1177/23727322231196867

Pedersini, C.A., Miller, N.P., Gandhi, T., Gilad-Gutnick, S., Mahajan, V., Sinha, P., Rokers, B., (2023). White Matter Plasticity Following Cataract Surgery in Congenitally Blind Patients. Proceedings of the National Academy of Sciences, 120(19) e2207025120. https://doi.org/10.1073/pnas.2207025120

Vogelsang, L.*, Gilad-Gutnick, S.*, Ehrenberg, E., Yonas, A., Diamond, S., Held, R. and Sinha, P. (2018).  Potential downside of high initial visual acuity.  Proceedings of the National Academy of Sciences, 115 (44) 11333-11338. https://doi.org/10.1073/pnas.1800901115

*Equally contributing first-authors

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Media coverage

MIT News coverage of our DTI work

MIT News covers our DTI work

American Academy of Ophthalmology covers our HIA work

“Blurry baby vision bolsters brain development”

Engadget covers project prakash

“The fight against childhood blindness could lead to eagle-eyed robots”

Discover magazine covers our compressed faces work

“We’re good at recognizing faces”

MIT Brain and Cognitive Science covers our HIA work

Covers Project Prakash following publication of HIA work

India New England News covers Project Prakash

The gift of light, through science and service

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